What causes euvolemic hypernatremia?

Updated: Mar 17, 2020
  • Author: Zina Semenovskaya, MD; Chief Editor: Romesh Khardori, MD, PhD, FACP  more...
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Answer

See the list below:

  • Extrarenal losses - Increased insensible loss (eg, hyperventilation)

  • Renal losses - Central DI, nephrogenic DI

These patients appear euvolemic because most of the free water loss is from intracellular and interstitial spaces, with less than 10% occurring from the intravascular space. Typically, symptoms result if serum sodium level is more than 160-170 mEq/L.


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