Which medications in the drug class Antibiotics are used in the treatment of Gingivitis?

Updated: Jan 18, 2018
  • Author: James M Stephen, MD, FAAEM, FACEP; Chief Editor: Jeff Burgess, DDS, MSD  more...
  • Print


These agents are used to eradicate the bacterial infection that is the hallmark of ANUG. In the future, antibiotics also may be used to treat simple chronic gingivitis, but no current evidence exists to justify this practice. Treatment of gingivitis may be warranted if dental surgery is planned.

Penicillin VK (Veetids)

DOC in patients with ANUG who are not allergic to penicillin.

Erythromycin (EES, Ery-Tab, Erythrocin)

Alternative DOC for patients allergic to penicillin.

Minocycline microspheres (Arestin)

Used as an adjunct to scaling and root planing procedures for reduction of pocket depth in patients with adult periodontitis. May be used as part of a periodontal maintenance program that includes good oral hygiene and scaling and root planing.

Doxycycline (Periostat)

Inhibits protein synthesis and thus bacterial growth by binding to 30S and possibly 50S ribosomal subunits of susceptible bacteria. However, some studies have shown that doxycycline reduces elevated collagenase activity in gingival crevicular fluid of patients with adult periodontitis. Clinical significance of these findings is not known.

Clindamycin (Cleocin)

Alternative for penicillin-allergic patients, a popular choice for severe infections or those recalcitrant with penicillin.

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!