What is the role of medications in the etiology of gingivitis?

Updated: Jan 18, 2018
  • Author: James M Stephen, MD, FAAEM, FACEP; Chief Editor: Jeff Burgess, DDS, MSD  more...
  • Print
Answer

Drug-induced causes

  • The list of drugs that cause gingivitis and gingival bleeding is extensive.

  • Gingival bleeding may occur with the use of anticoagulants and fibrinolytic agents.

  • Phenytoin, oral contraceptive agents, and calcium channel blockers may cause gingival hyperplasia.

  • Gingivitis has been observed with use of protease inhibitors (eg, saquinavir, ritonavir), vitamin A and analogues, danazol, pentamidine, misoprostol, methotrexate, and gold compounds.

  • Gingivostomatitis has been observed in exposure to arsenic, gold, bismuth, mercury, nickel, sulfur dioxide, lead, thallium, zinc, methyl violet, and topical chlorhexidine.


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!