What is the role of brain natriuretic peptide (BNP) assays in risk stratification and outcome prediction for congestive heart failure (CHF)?

Updated: Jan 08, 2018
  • Author: Donald Schreiber, MD, CM; Chief Editor: Erik D Schraga, MD  more...
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Many groups have evaluated the utility of brain natriuretic peptide (BNP) and NT-proBNP levels for risk stratification and as predictors of adverse clinical outcomes. [41, 42, 43, 44, 45, 46] The studies differ in patient populations, definition of clinical endpoints, and durations of follow-up. However, most studies have consistently demonstrated a direct correlation between BNP and NT-proBNP levels and clinical outcomes in patients with congestive heart failure (CHF). The natriuretic peptides may also be useful as triage instruments to help guide the emergency physician.

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