What is the role of growth factor and cell therapy in the treatment of peripheral vascular disease (PVD)?

Updated: Dec 31, 2017
  • Author: Everett Stephens, MD; Chief Editor: Erik D Schraga, MD  more...
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Answer

An emerging treatment for peripheral vascular disease (PVD) is the use of growth factor (delivered as genes or proteins) and cell therapy. The delivery of growth factors or cells to the ischemic tissue can locally stimulate the regeneration of the functional vasculature network, reperfuse the ischemic tissue, and salvage the limb. [18]

A guideline on management of patients with lower-extremity PAD has been formulated by the American Heart Association and the American College of Cardiology (see Guidelines). [19]


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