What is the role of emboli in the pathophysiology of peripheral vascular disease (PVD)?

Updated: Dec 31, 2017
  • Author: Everett Stephens, MD; Chief Editor: Erik D Schraga, MD  more...
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Answer

Emboli, the most common cause of sudden ischemia, usually are of cardiac origin (80%); they also can originate from proximal atheroma, tumor, or foreign objects. Emboli tend to lodge at artery bifurcations or in areas where vessels abruptly narrow. The femoral artery bifurcation is the most common site (43%), followed by the iliac arteries (18%), the aorta (15%), and the popliteal arteries (15%).


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