What causes peripheral vascular disease (PVD)?

Updated: Dec 31, 2017
  • Author: Everett Stephens, MD; Chief Editor: Erik D Schraga, MD  more...
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Answer

PVD, also known as arteriosclerosis obliterans, is primarily the result of atherosclerosis. The atheroma consists of a core of cholesterol joined to proteins with a fibrous intravascular covering. The atherosclerotic process may gradually progress to complete occlusion of medium-sized and large arteries. The disease typically is segmental, with significant variation from patient to patient.


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