Which medications may cause myopathy?

Updated: Dec 28, 2017
  • Author: Courtney A Bethel, MD, MPH; Chief Editor: Barry E Brenner, MD, PhD, FACEP  more...
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Answer

Drug-induced or toxic causes of myopathy include use of the following [4] :

  • Steroids (especially with prolonged high doses, divided doses over 25 mg/day, fluorinated steroid use)
  • Zidovudine (AZT)
  • Lovastatin and other statins [5, 6]
  • Cocaine
  • Colchicine
  • Amiodarone and other agents that inhibit CYP3A4 when combined with simvastatin

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