Which tests are performed in the evaluation of myopathies?

Updated: Dec 28, 2017
  • Author: Courtney A Bethel, MD, MPH; Chief Editor: Barry E Brenner, MD, PhD, FACEP  more...
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Answer

The following laboratory tests may be used to evaluate patients with myopathies:

  • Creatine kinase (CK) levels with isoenzymes
  • Levels of electrolytes, calcium, and magnesium
  • Serum myoglobin levels
  • Serum creatinine and blood urea nitrogen levels
  • Urinalysis: Myoglobinuria indicated by positive urinalysis with few red blood cells on microscopic evaluation
  • Complete blood count
  • Erythrocyte sedimentation rate
  • Thyroid function tests
  • Aspartate aminotransferase levels

Other studies may include the following:

  • Electrocardiography
  • Antinuclear antibody levels
  • Genetic testing
  • Electromyography
  • Magnetic resonance imaging (to assess complications or rule out neurologic disease)
  • Muscle biopsy

See Workup for more detail.


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