When are antibiotics indicated for treatment of superficial thrombophlebitis?

Updated: Apr 17, 2019
  • Author: Khanjan H Nagarsheth, MD, MBA; Chief Editor: Vincent Lopez Rowe, MD  more...
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Answer

Antibiotics are not routinely indicated for treatment of superficial thrombophlebitis, in that the erythema and tenderness are local inflammatory reactions, not allergic reactions. However, if suppurative thrombophlebitis may be present, then antibiotics should cover skin flora and anaerobic organisms, especially if an abscess is present. One should also consider coverage with vancomycin for methicillin-resistant Staphylococcus aureus (MRSA) if the local population warrants this.


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