Which lab studies help identify hypercoagulable states in superficial thrombophlebitis?

Updated: Apr 17, 2019
  • Author: Khanjan H Nagarsheth, MD, MBA; Chief Editor: Vincent Lopez Rowe, MD  more...
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Answer

Blood tests rarely are helpful in the diagnosis of thrombophlebitis, except in those patients at risk for an underlying hypercoagulable state. Several common hypercoagulable states, including the following, can be identified through laboratory studies:

  • Resistance to activated protein C (most often due to factor V Leiden)
  • Protein C deficiency
  • Protein S deficiency
  • Antithrombin III deficiency
  • Antiphospholipid antibodies
  • Prothrombin gene 2010-a mutation (factor II mutation)

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