When are thrombolytics or anticoagulants indicated for the treatment of superior vena cava syndrome (SVCS)?

Updated: Mar 26, 2018
  • Author: Todd A Nickloes, DO, FACOS; Chief Editor: Vincent Lopez Rowe, MD  more...
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Answer

When SVCS is due to thrombus around a central venous catheter, patients may be treated with thrombolytics (eg, streptokinase, urokinase, or recombinant tissue-type plasminogen activator) or anticoagulants (eg, heparin or oral anticoagulants). Removal of the catheter, if possible, is another option, and it should be combined with anticoagulation to prevent embolization. [6, 16] . These agents are most effective when patients are treated within 5 days after the onset of symptoms.


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