What is the role of chemotherapy in the treatment of superior vena cava syndrome (SVCS)?

Updated: Mar 26, 2018
  • Author: Todd A Nickloes, DO, FACOS; Chief Editor: Vincent Lopez Rowe, MD  more...
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Answer

Chemotherapy may be preferable to radiation for patients with chemosensitive tumors. [25] In 1983, Maddox et al reported on 56 patients with small-cell lung cancer who presented with SVCS. Correction of SVCS was obtained in 9 (56%) of 16 patients treated with radiation therapy alone, in 23 (100%) of 23 given chemotherapy, and in 5 (83%) of 6 who received combined therapy. [26]


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