What is the prognosis of superior vena cava syndrome (SVCS)?

Updated: Mar 26, 2018
  • Author: Todd A Nickloes, DO, FACOS; Chief Editor: Vincent Lopez Rowe, MD  more...
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Survival in patients with SVCS depends mainly on the course of the underlying disease. No mortality, per se, results directly from mild venous congestion.

In patients with benign SVCS, life expectancy is unchanged. If SVCS is secondary to a malignant process, patient survival correlates with tumor histology. Patients with signs and symptoms of laryngeal and cerebral edema have the most life-threatening manifestations of SVCS and are in danger of sudden death.

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