What is the role of xenografts in the treatment of diabetic skin ulcers?

Updated: Oct 15, 2020
  • Author: Tanzim Khan, DPM; Chief Editor: Romesh Khardori, MD, PhD, FACP  more...
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oasis/" target="_blank">Oasis (Smith & Nephew) is a xenogeneic, acellular collagen matrix derived from porcine small intestinal submucosa that allows an extracellular matrix and natural growth factors to remain intact. 

Integra (Integra LifeSciences) is a bilayered skin substitute that is composed of bovine collagen and chondroitin 6-sulfate for dermal regeneration. The silicone top layer mimics epidermis, providing protection and preventing moisture loss. 

Primatrix (Integra LifeSciences) is a collagen-based dermal repair scaffold that is derived from fetal bovine dermis. There is an option of obtaining this graft with ionic silver impregnation, which provides antimicrobial coverage for contaminated wounds.

ACell (ACell) is an acellular wound scaffold derived from porcine urinary bladder matrix that can be obtained in either fenestrated sheet form or in a particulate form that is useful for deep and tunneling wounds.

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