What is the role of debridement in the treatment of diabetic foot ulcers?

Updated: Oct 15, 2020
  • Author: Tanzim Khan, DPM; Chief Editor: Romesh Khardori, MD, PhD, FACP  more...
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Débridement is indicated for preventing ulceration of nonviable and/or infected tissue. Hyperkeratotic tissue, fibrin, eschar, biofilm, and necrotic tissue need to be removed from the wound and periwound to facilitate wound healing. It is not uncommon for the wound to be larger in size following debridment, especially after the initial débridement. Chronic wounds such as diabetic foot ulcers are often arrested in the healing cascade, and with débridement there is the creation of a reservoir of growth factors to assist the wound in moving forward in healing. These include platelet-derived growth factor, which is excreted by small vessels in the fresh, bleeding edges of a debrided wound. [58]

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