What are the diagnostic criteria for thromboangiitis obliterans (TAO) (Buerger disease)?

Updated: Jul 27, 2020
  • Author: Naiem Nassiri, MD; Chief Editor: Vincent Lopez Rowe, MD  more...
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Answer

Because a firm diagnosis of thromboangiitis obliterans (TAO; also referred to as Buerger disease), is difficult to establish, a number of different diagnostic criteria have been proposed. [7] In 1990, Olin et al asserted that the following criteria must be met for the diagnosis to be made with reasonable certainty [8] :

  • Age younger than 45 years
  • Current (or recent) history of tobacco use
  • Presence of distal extremity ischemia (indicated by claudication, pain at rest, ischemic ulcers, or gangrene) documented by noninvasive vascular testing
  • Exclusion of autoimmune diseases, hypercoagulable states, and diabetes mellitus by laboratory tests
  • Exclusion of a proximal source of atheroemboli by echocardiography and arteriography
  • Consistent arteriographic findings in the clinically involved and noninvolved limbs

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