What is the role of fesoterodine in the treatment of overactive bladder (OAB) in children?

Updated: Apr 01, 2019
  • Author: Pamela I Ellsworth, MD; Chief Editor: Edward David Kim, MD, FACS  more...
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Answer

Fesoterodine was evaluated for pharmacokinetics and tolerability in a dose-escalation study in children with overactive bladder, and it was demonstrated that oral administration of fesoterodine in pediatric patients (>25 kg) with idiopathic OAB or neurogenic detrusor overactivity produced steady-state plasma 5-hydroxy-methyltolterodine exposures similar to those in adults. The doses given were well tolerated. [40]


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