What is the role of trospium chloride (Sanctura) in the treatment of overactive bladder (OAB) in children?

Updated: Apr 01, 2019
  • Author: Pamela I Ellsworth, MD; Chief Editor: Edward David Kim, MD, FACS  more...
  • Print
Answer

Trospium chloride (Sanctura), another agent used in adults, has been studied in a small series of children, with dosages ranging from 10 to 25 mg/d, divided into 2 doses daily; overall, 32% of the subjects had an excellent response to the drug, 42% a good response, and 8% a fair response. [34]  Detrusor overactivity resolved completely in 35%. Trospium is currently approved for use in the United States for adults in a dose of 20 mg orally twice daily. No dosing guidelines or safety and efficacy information are available regarding its use in children.


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!