What is the role of imipramine in the treatment of overactive bladder (OAB) in children?

Updated: Apr 01, 2019
  • Author: Pamela I Ellsworth, MD; Chief Editor: Edward David Kim, MD, FACS  more...
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Answer

Imipramine has been studied for the treatment of refractory daytime incontinence in children. One hundred and three patients (55 males and 48 females) were included in the study. Of those children with complete follow-up (n = 83), 44 (53%) experienced complete treatment response. Side effects were reported by 11 out of 83 (13.3%) patients. A side effects were nearly twice as common (26.1%) among the 23 children with a partial response to treatment. [33]


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