Which medications are used in the treatment of chronic bacterial prostatitis (CBP)?

Updated: Jan 15, 2019
  • Author: Samantha D Kraemer, MD; Chief Editor: Edward David Kim, MD, FACS  more...
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Answer

Oral antimicrobial agents are the mainstay of treatment for chronic bacterial prostatitis (CBP), with the most effective medications being fluoroquinolones and trimethoprim-sulfamethoxazole (TMP/SMX). Empiric antimicrobial therapy must be comprehensive and should cover all likely pathogens in the context of the clinical setting.

Alpha blockers, which relax smooth muscle in the bladder neck, can help to decrease recurrences of CBP by diminishing urinary obstruction due to prostate enlargement or congestion secondary to inflammation.


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