What is the risk of prostate cancer in patients with chronic bacterial prostatitis (CBP)?

Updated: Jan 15, 2019
  • Author: Samantha D Kraemer, MD; Chief Editor: Edward David Kim, MD, FACS  more...
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Answer

There is concern that clinical chronic prostatitis may be a risk factor for prostate cancer. Two separate meta-analyses and other large case-control studies have estimated a 60% increased risk of prostate cancer in patients with symptomatic prostatitis in white men. [25] However, African Americans have been shown in one study to actually have a slightly decreased risk of prostate cancer with symptomatic prostatitis. [25]

Some studies report that men with prostate cancer have histological prostatic inflammation 4-5 times more often than men without prostate cancer. Other studies have suggested that histological prostatic inflammation in benign prostate tissue specimens from asymptomatic men are associated with decreased future prostate cancer risk. [25] As mentioned previously, prostatic inflammation is a nonspecific finding, and its relation to prostate cancer is also unclear.


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