What are the ESMO risk classifications of prostate cancer?

Updated: Jan 14, 2019
  • Author: Lanna Cheuck, DO; Chief Editor: Edward David Kim, MD, FACS  more...
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Guidelines from the European Society for Medical Oncology (ESMO) recommend classifying localized prostate cancer as follows, in order to guide prognosis and therapy [5] :

  • Low risk: T1–T2a and Gleason score ≤6 and PSA ≤10
  • Intermediate risk: T2b and/or Gleason score 7 and/or PSA 10-20
  • High risk: ≥T2c or Gleason score 8-10 or PSA >20

The ESMO recommends that patients with intermediate- or high-risk disease have nodal staging using CT, MRI, choline positron emission tomography/CT (PET/CT), or pelvic nodal dissection. Patients with intermediate- or high-risk disease should be staged for metastases using technetium bone scan and thoracoabdominal CT scan, whole-body MRI, or choline PET/CT. [5]

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