How is prostate cancer staged?

Updated: Jan 14, 2019
  • Author: Lanna Cheuck, DO; Chief Editor: Edward David Kim, MD, FACS  more...
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Answer

Answer

Staging of prostate cancer is based on the following five key pieces of information [6] :

  • The extent of the primary tumor (T category)
  • Whether the cancer has spread to nearby lymph nodes (N category)
  • The absence or presence of distant metastasis (M category)
  • The PSA level at the time of diagnosis
  • The Grade Group, based on prostate biopsy (or surgery); see  Histologic Findings.

Table. Prognostic Groups for Prostate Cancer (Open Table in a new window)

Group

Tumor

Node

M

PSA (ng/mL)

Grade Group

Stage I

cT1a-c

N0

M0

< 10

1

cT2a

N0

M0

< 10

1

pT2

N0

M0

< 10

1

Stage IIA

cT1a-c

N0

M0

10 to < 20

1

cT2a

N0

M0

10 to < 20

1

pT2

N0

M0

10 to < 20

1

cT2c

N0

M0

< 20

1

Stage IIB

T1-2

N0

M0

< 20

2

Stage IIC

T1-2

N0

M0

< 20

3

T1-2

N0

M0

< 20

4

Stage IIIA

T1-2

N0

M0

≥ 20

1-4

Stage IIIB

T3-4

N0

M0

Any

1-4

Stage IIIC

Any T

N0

M0

Any

5

Stage IVA

Any T

N1

M0

Any

Any

Stage IVB

Any T

Any N

M1

Any

Any


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