What is the role of MDP bone scan in the workup of prostate cancer?

Updated: Jan 14, 2019
  • Author: Lanna Cheuck, DO; Chief Editor: Edward David Kim, MD, FACS  more...
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According to the National Comprehensive Cancer Network (NCCN), technetium-99m-methyl diphosphonate (MDP) bone scan is indicated in the initial evaluation of patients at high risk for skeletal metastases, as indicated by any of the following [23] :

  • T1 disease, PSA ≥20
  • T2 disease, PSA ≥10
  • Gleason score ≥8
  • T3/T4 disease
  • Symptoms suggestive of osseous metastasis

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