What are the ACS guidelines on prostate cancer screening?

Updated: Jan 14, 2019
  • Author: Lanna Cheuck, DO; Chief Editor: Edward David Kim, MD, FACS  more...
  • Print


The American Cancer Society (ACS) recommends that asymptomatic men with at least a 10-year life expectancy should be given an opportunity to make an informed decision with their health care provider after receiving information on the uncertainties, risks, and benefits of screening PSA evaluation. The recommended age at which men should receive this information varies by prostate cancer risk, as follows [1] :

  • Age 50 for those at average risk of developing prostate cancer
  • Age 45 for those at high risk, including African Americans and men with a first-degree relative (father, brother, son) diagnosed with prostate cancer before age 65
  • Age 40 for those at higher risk (more than one first-degree relative diagnosed with prostate cancer at an early age)

Men who decide to be screened should be tested with a PSA test. A DRE may also be done as a part of screening. If screening does not detect cancer, the time between subsequent screenings depends on the PSA results, as follows [1] :

  • < 2.5 ng/ml – Retesting may be done every 2 years
  • ≥2.5 ng/ml – Retesting should be done annually

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!