Which men have the highest prevalence of prostate cancer?

Updated: Jan 14, 2019
  • Author: Lanna Cheuck, DO; Chief Editor: Edward David Kim, MD, FACS  more...
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Answer

Answer

Prostate cancer is rarely diagnosed in men younger than 40 years, and it is uncommon in men younger than 50 years.

Prevalence rates of prostate cancer remain significantly higher in African-American men than in white men, while the prevalence in Hispanic men is similar to that of white men. Hispanic men and African-American men tend to present with more advanced disease, a situation that is most likely related to external (eg, income, education, insurance status) and cultural factors. In addition, African-American men generally have higher levels of testosterone, which may contribute to the higher incidence of carcinoma in that population. [8, 9]

Mutations that appear specific to, or more common in, African-American patients have been identified in aggressive prostate tumors. Further research will be needed to determine whether these mutations factor into the racial differences in incidence and clinical outcome that are seen in prostate cancer. [10]


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