What is the role of lab tests in the workup of prostate cancer?

Updated: Jan 15, 2019
  • Author: Lanna Cheuck, DO; Chief Editor: Edward David Kim, MD, FACS  more...
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Answer

Answer

PSA screening: Controversy exists regarding PSA level cutoffs and reference ranges

DRE: Serial examinations are best; clues to the patient’s condition in conjunction with PSA levels include presence of a nodule, as well as asymmetry, texture difference(s), and bogginess of the prostate, seminal vesicles, and adjacent organs

Biopsy and histologic examination: These aid in the diagnosis and help to determine the Gleason score; a biopsy can also help differentiate a cyst or calculus from cancer foci


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