What is the role of subintestinal submucosa (SIS) in the treatment of iatrogenic ureteral injury?

Updated: Nov 12, 2020
  • Author: Sandip P Vasavada, MD; Chief Editor: Bradley Fields Schwartz, DO, FACS  more...
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The use of new technology may change the management of distal ureteral injuries entirely. With the introduction of subintestinal submucosa (SIS) to be used as a tissue scaffold, a new modality to treat ureteral injuries has emerged. While no current studies are being performed using SIS for the treatment of distal ureteral injuries, the placement of SIS may serve as a healing bridge between 2 injured ureteral ends. Although SIS will not drastically affect the management of short ureteral injuries or strictures, it may be useful in treating longer ureteral defects.

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