Which dietary modifications are used in the treatment of metastatic and advanced prostate cancer?

Updated: Dec 29, 2020
  • Author: Martha K Terris, MD, FACS; Chief Editor: Edward David Kim, MD, FACS  more...
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Because a high-fat diet is linked with a higher incidence of prostate cancer, a low-fat diet may be beneficial for patients at high risk of developing prostate cancer (namely those with positive family history, black males) and for patients undergoing treatment for advanced prostate cancer. [13] In addition, tomatoes, broccoli, green tea, soy, lycopenes, licorice root, selenium, and antioxidants have all been hypothesized to be beneficial.

However, the Physicians' Health Study II, a long-term, randomized, controlled trial involving male physicians, found that neither vitamin E nor C supplementation reduced the risk of cancer—prostate or otherwise. [14] Similarly, the Selenium and Vitamin E Cancer Prevention Trial (SELECT), a randomized, placebo-controlled trial involving 35,533 relatively healthy study participants from 427 US sites, found that neither selenium nor vitamin E (alone or in combination), at the doses and formulations used, prevented prostate cancer. [15] (See also Prostate Cancer and Nutrition.)

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