What is the role of biopsy in the workup of metastatic and advanced prostate cancer?

Updated: Dec 29, 2020
  • Author: Martha K Terris, MD, FACS; Chief Editor: Edward David Kim, MD, FACS  more...
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Transrectal ultrasonography (TRUS)-guided needle biopsy of the prostate is indicated for tissue diagnosis in patients who present with elevated prostate-specific antigen (PSA) levels or abnormal digital rectal examination findings. This study should be repeated, if indicated, to determine local recurrence. (See Techniques of Local Anesthesia for Prostate Procedures and Biopsies for more information.)

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