Which physical findings are characteristic of metastatic and advanced prostate cancer?

Updated: Dec 29, 2020
  • Author: Martha K Terris, MD, FACS; Chief Editor: Edward David Kim, MD, FACS  more...
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Physical examination findings of adenopathy, lower-extremity edema, and bony tenderness may indicate metastatic disease. In addition, obliteration of the lateral sulcus or seminal vesical involvement found during rectal examination often indicates locally advanced disease.

Neurologic examination, including determination of external anal sphincter tone, should be performed to help detect possible spinal cord compression.

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