What is the role of oxybutynin chloride in the treatment of neurogenic bladder?

Updated: Dec 06, 2018
  • Author: Bradley C Gill, MD, MS; Chief Editor: Edward David Kim, MD, FACS  more...
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Answer

Answer

Oxybutynin chloride has both anticholinergic and direct smooth-muscle relaxant effects on urinary bladder. It provides a local anesthetic effect on irritable bladder. Urodynamic studies have shown that oxybutynin increases bladder size, decreases frequency of symptoms, and delays initial desire to void.


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