Which antibiotics are contraindicated for the treatment of urinary tract infection (UTI) during pregnancy?

Updated: Aug 17, 2021
  • Author: Raisa O Platte, MD, PhD; Chief Editor: Edward David Kim, MD, FACS  more...
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Some antibiotics should not be used during pregnancy, because of their effects on the fetus. These include the following:

  • Tetracyclines (adverse effects on fetal teeth and bones and congenital defects)

  • Trimethoprim in the first trimester (facial defects and cardiac abnormalities)

  • Chloramphenicol (gray syndrome)

  • Sulfonamides in the third trimester (hemolytic anemia in mothers with glucose-6-phosphate dehydrogenase [G6PD] deficiency, jaundice, and kernicterus)

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