How is nocturnal enuresis treated in urinary incontinence?

Updated: Sep 23, 2019
  • Author: Sandip P Vasavada, MD; Chief Editor: Edward David Kim, MD, FACS  more...
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Such basic measures as evening fluid restriction and daytime bladder training can be beneficial. [85] Nasal DDAVP at 10-40 mg decreases nighttime urine production. Imipramine (2 mg/kg/d) has been one of the most common pharmacologic therapies. Oxybutynin and other anticholinergics have been used.

Ephedrine was found to be moderately beneficial in one trial. Some believe that this agent works by increasing urethral alpha-sympathetic tone.

Although pharmacologic treatment can help, the underlying disorder often returns after discontinuation. Conditioning therapy with moisture-sensitive alarms are effective. Positive results usually persist even after the device is removed.

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