What is the pathophysiology of urge urinary incontinence in men?

Updated: Mar 19, 2019
  • Author: Sandip P Vasavada, MD; Chief Editor: Edward David Kim, MD, FACS  more...
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Answer

In males, early obstruction due to benign prostatic hyperplasia (BPH) may result in urge incontinence. [22] The pathophysiology of BPH is poorly understood. Relative obstruction develops because of mechanical factors, dynamic factors, and detrusor alterations.

Androgen-induced enlargement of nodules of glandular tissue comprises the mechanical portion of the disorder. The dynamic component is related to increased alpha tone in prostatic and urethral smooth muscle. Detrusor dysfunction may consist of impaired contractility, detrusor overactivity, or both. In severe cases of obstruction, retention and overflow incontinence may develop, and the upper urinary tract can become damaged.


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