What are the benefits of partial nephrectomy nephron-sparing surgery (NSS) in the treatment of inconclusive solid renal masses?

Updated: Mar 31, 2019
  • Author: Reza Ghavamian, MD; Chief Editor: Bradley Fields Schwartz, DO, FACS  more...
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Next, differential diagnoses of incidentally detected solid renal masses include oncocytoma, angiomyolipoma, transitional cell carcinoma, complex cyst, or a hypertrophied column of Bertin. The characteristics of most of these entities on the imaging studies, most commonly CT scanning, and their clinical presentation allow for their differentiation. However, consider solid lesions that radiographically enhance with intravenous contrast to be RCC until proven otherwise. Of these lesions, 10-15% are oncocytomas. Needle biopsies have not been shown to be reliable and are associated with high false-negative rates. Therefore, although an operative approach is indicated, NSS allows for equivalent cancer treatment while minimizing the risk of nephron loss in the 10% of patients with a benign lesion.

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