Which histologic findings are characteristic of primary bladder cancer?

Updated: Apr 03, 2019
  • Author: E Jason Abel, MD; Chief Editor: Bradley Fields Schwartz, DO, FACS  more...
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Primary solitary bladder cancer is a common indication for consideration of partial cystectomy. More than 90% of bladder cancers are urothelial carcinomas. Of these, 70% are papillary (see the image below), 10% are nodular, and 20% are mixed. When confined to the urothelium, the cancer is called carcinoma in situ. The other 10% of tumors are composed predominantly of squamous cell carcinomas (3-7%) and adenocarcinomas (2%). Secondary metastatic disease in the bladder accounts for less than 1% of all bladder cancers.

Papillary bladder tumors such as this one are typi Papillary bladder tumors such as this one are typically of low stage and grade (Ta-G1). Courtesy of Abbott and Vysis Inc.

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