What is the role of partial cystectomy in the treatment of pheochromocytoma of the bladder?

Updated: Apr 03, 2019
  • Author: E Jason Abel, MD; Chief Editor: Bradley Fields Schwartz, DO, FACS  more...
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Answer

Pheochromocytoma of the bladder is a rare neoplasm, accounting for less than 1% of all bladder tumors. Pheochromocytoma is a tumor of neuroendocrine origin that tends to be functional. Typical presenting symptoms include hematuria and symptoms related to catecholamine secretion, including paroxysmal hypertension and micturition-related headache, palpitations, and syncope. In a recent systematic review, Beilan et al reported that partial cystectomy was the primary treatment for approximately 70% of these tumors, with good symptomatic control and low morbidity. Irrespective of treatment, at a mean follow-up of 35 months, 14.2% had disease recurrence, 9.4% had metastasis, and 56.6% had no evidence of disease. Of note, surgical treatment (whether partial or radical cystectomy) is rarely curative if the disease is metastatic. [13]


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