What is the role of partial cystectomy in the treatment of squamous cell carcinoma of the bladder?

Updated: Apr 03, 2019
  • Author: E Jason Abel, MD; Chief Editor: Bradley Fields Schwartz, DO, FACS  more...
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Squamous cell carcinoma has a poor prognosis and is not responsive to chemotherapy and radiation. Although some series describe the feasibility of partial cystectomy, this approach has not been studied extensively because of its low prevalence in the western world (3-7% in the United States). [9] In contrast, 75% of all bladder cancers in Egypt are of squamous cell derivation because of S. hematobium infection. In some reports, bilharzial bladder cancer (bladder cancer associated with Schistosomiasis) has a similar prognosis to transitional cell cancer when compared stage-for-stage, but whether this is true for nonbilharzial squamous cell carcinoma is unclear.

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