What is the role of pharmacologic therapy in the treatment of erectile dysfunction (ED)?

Updated: Oct 14, 2020
  • Author: Edward David Kim, MD, FACS; Chief Editor: Edward David Kim, MD, FACS  more...
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An increasing array of medications is available to assist in the management of ED. New agents are still undergoing clinical testing, and more are in the early phases of development. Medications currently being developed include dopaminergic and melanocortin receptor agonists, second-generation phosphodiesterase 5 (PDE5) inhibitors, rho-kinase inhibitors, soluble guanylate cyclases, and maxi-k channel activators. [84]  

For any medication to be effective, the physiologic components involved in the erectile process must be functional. Serious impairments render the medication either completely or partially ineffective.

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