What is the role of radical cystectomy in the treatment of bladder cancer?

Updated: Feb 23, 2021
  • Author: Kara N Babaian, MD, FACS; Chief Editor: Bradley Fields Schwartz, DO, FACS  more...
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Answer

Although radical cystectomy is typically reserved for muscle-invasive disease, it is also appropriately used to treat some patients with high-risk, non–muscle-invasive bladder cancer, including CIS. Indications in non–muscle-invasive disease include the following:

  • Tumor bulk so substantial that complete eradication of tumor is not feasible endoscopically
  • Prostatic urethra involvement
  • CIS or T1 high-grade tumor persistence despite adequate intravesical management

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