What is the role of docetaxel in the treatment of bladder cancer?

Updated: Feb 23, 2021
  • Author: Kara N Babaian, MD, FACS; Chief Editor: Bradley Fields Schwartz, DO, FACS  more...
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Answer

Intravesical docetaxel appears to be a promising agent for BCG-refractory non–muscle-invasive bladder cancer; adding maintenance treatments of docetaxel may increase the duration of recurrence-free survival. Barlow et al reported that 32 of 54 patients with BCG-refractory bladder cancer showed a complete response to 6 weekly treatments of intravesical docetaxel. [104] Median time to recurrence was 39.3 months in responders treated with maintenance docetaxel, compared with 19 months in those who did not receive maintenance therapy.


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