What are the NCCN recommendations for treatment of CIS bladder cancer?

Updated: Feb 23, 2021
  • Author: Kara N Babaian, MD, FACS; Chief Editor: Bradley Fields Schwartz, DO, FACS  more...
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The NCCN recommendations for CIS are as follows [1] :

  • Resection followed by intravesical therapy with BCG once a week for 6 weeks, followed by a rest period of 6 weeks

  • Full re-evaluation at week 12 (ie, 3 months) after the start of therapy

  • If the patient is unable to tolerate BCG, intravesical mitomycin C may be administered (however, most patients can tolerate BCG with dose reductions and anticholinergic medication)

  • Follow-up is similar to that for T1 and Ta high-grade tumors

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