What are the NCCN and EAU recommendations for the treatment of high-grade Ta bladder tumors?

Updated: Feb 23, 2021
  • Author: Kara N Babaian, MD, FACS; Chief Editor: Bradley Fields Schwartz, DO, FACS  more...
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Answer

NCCN and European Association of Urology (EAU) recommendations for treatment of high-grade Ta tumors are as follows [69, 1] :

  • TURBT should be repeated if there is incomplete resection; if no muscle is present in the specimen, strongly consider repeating resection. In addition, repeat TURBT has prognostic, therapeutic, and surveillance indications: Up to 40-70% of patients will have residual bladder cancer at repeat TURBT performed within 2-6 weeks after initial TURBT

  • Intravesical immunotherapy bacillus Calmette-Guérin (BCG) after TURBT is recommended and is superior to intravesical chemotherapy for preventing tumor recurrence [143, 69]


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