What is the role of avelumab (Bavencio) in the treatment of metastatic bladder cancer?

Updated: Feb 23, 2021
  • Author: Kara N Babaian, MD, FACS; Chief Editor: Bradley Fields Schwartz, DO, FACS  more...
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Answer

Avelumab (Bavencio) was also granted accelerated approval in April 2017, for advanced urothelial carcinoma in patients progressing during or following platinum-containing chemotherapy. Approval was based on the JAVELIN solid tumor trial, which comprised 2 cohorts with 44 patients and 200 patients, respectively. The data from both cohorts were pulled together and showed that 161 patients with a follow-up of > 6 months had an overall response rate of 16.1%. [138]


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