What is the impact on survival of a longer interval between diagnosis and radical cystectomy for bladder cancer?

Updated: Feb 23, 2021
  • Author: Kara N Babaian, MD, FACS; Chief Editor: Bradley Fields Schwartz, DO, FACS  more...
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Answer

Emerging retrospective data from multiple institutions suggest that a longer interval from the time of diagnosis to radical cystectomy can adversely affect pathologic stage and survival. [117] For example, at the University of Pennsylvania, patients who underwent radical cystectomy within 12 weeks of the diagnosis had a lower incidence of advanced pathologic stage (42% vs 84% with extravesical disease), lower incidence of positive lymph nodes, and an increased 3-year survival rate (62% vs 35% with extravesical disease). [118]


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