When is lymph node dissection indicated in the treatment of bladder cancer?

Updated: Feb 23, 2021
  • Author: Kara N Babaian, MD, FACS; Chief Editor: Bradley Fields Schwartz, DO, FACS  more...
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Answer

Much controversy exists regarding the optimal extent of the lymph node dissection that should accompany cystectomy. It is clear that at minimum, a meticulous standard dissection should be performed.

While a number of retrospective studies demonstrate no difference in overall survival with standard versus extended lymph node dissection, a growing body of evidence suggests that more extended node dissection may improve survival in both lymph node–positive and lymph node–negative disease. The first prospective, randomized trial to address this question, sponsored by the Southwest Oncology Group (SWOG), is currently enrolling patients. [96]


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