What is the significance of stage and grade in bladder cancer?

Updated: Feb 23, 2021
  • Author: Kara N Babaian, MD, FACS; Chief Editor: Bradley Fields Schwartz, DO, FACS  more...
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Stage and grade are critical to the likelihood of cancer recurrence and progression in persons with bladder cancer who are treated with local therapy.

In 2004, the International Society of Urologic Pathologists and World Health Organization adopted low-grade or high-grade designations. Papillary urothelial neoplasia of low malignant potential (PUNLMP) has also been added as a designation. [5]

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