What is the likelihood of bladder cancer metastasis?

Updated: Feb 23, 2021
  • Author: Kara N Babaian, MD, FACS; Chief Editor: Bradley Fields Schwartz, DO, FACS  more...
  • Print
Answer

As many as 50% of patients with muscle-invasive bladder cancer may have occult metastases that become clinically apparent within 5 years of initial diagnosis and around 5% will have distant metastasis at the time of initial diagnosis. [80] Most patients with overt metastatic disease die within 2 years despite chemotherapy. Approximately 25-30% of patients with only limited regional lymph node metastasis discovered during cystectomy and pelvic lymph node dissection may survive beyond 5 years. Metastasis can occur through lymphatic spread, most commonly affecting the pelvic lymph nodes, or through hematogenous spread to the liver, lung, or bone. [80]


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!